Are You Worried About An Enlarged Prostate Or Other Prostate Problem?
In older men, the inner part of the prostate around the urethra may continue to grow, a condition called benign prostatic hyperplasia (BPH) – also referred to as an enlarged prostate or swollen prostate. Perhaps a fourth of men have some degree of hyperplasia by the time they reach their fifties. By the eighth decade, over 90% of males will have prostatic hyperplasia (according to the American Urological Association).
However, in only a small number of cases (about 10%) will this hyperplasia be symptomatic and severe enough to require any surgical or medical therapy. The mechanism for hyperplasia may be related to an accumulation of dihydrotestosterone in the prostate, which then binds to nuclear hormone receptors which then trigger the growth. The normal prostate weighs 20 to 30 gm, but most prostates with nodular hyperplasia can weigh as much as 50 to 100 gm. And nodular hyperplasia is NOT a precursor to cancer. A mildly increased PSA (4 to 10 ng/mL) in a patient with a very large prostate can be due to either nodular hyperplasia, or to prostatitis, rather than cancer.